| Abingdon @ South Fulton (VIT) |
| The Commandos open against the Rebels. The Rebels were a playoff team last year. |
| Annawan-Wethersfield @ Peoria Heights |
| A & W a first year coop, no not the root beers, in the Patriot Bowl. The Titans are the new team in the Northeast. |
| Stark County @ Cambridge |
| Old rivals, playoff rivals a big game to open up the season in Viking country. |
| AlWood-ROWVA @ Galva/Williamsfield |
| A game for two teams wanting a better season than last year. |
| West Central @ United (Monmouth) |
| This is as close to the old Bi-County as it gets in these times. |
| North Fulton @ Lewistown |
| Rematch from last year's playoff teams, with new players. |
| Elmwood-Brimfield @ Princeville |
| Two neighboring teams that haven't played each other for years. |
| West Prairie @ Illini West |
| This is a real hillbilly wedding everyone is related in some way. |
| West Hancock @ Aledo-Westmer |
| Two schools becoming great rivals a rematch from a year ago. |
| Pittsfield G.P. @ Athens |
| A long football tradition comes to a program in it's third year. |
| Bushnell-PC/Avon @ Beardstown |
| Spartans come off a good year last season, Tigers want to bounce back from a less stellar season. |
| Havana @ Rushville/Industry |
| Will the Ducks out fly the Rockets? The Rockets start another season to continue their long playoff streak. |
| PORTA @ Pleasant Plains |
| After a big Blue Jay year last season, the Cardinals want to be noticed. |
| Unity @ Camp Point Cent/SE |
| Two old rivals ready to renew the game in 2008. |
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